Doloteffin – with Devil's claw
A natural way to effectively support treatment of degenerative disorders of the locomotor system.


Why to take Doloteffin – instead of other products ?

Devil's claw in Doloteffin has several advantages and benefits:


  • Clinical efficacy has been known for many years.
  • relieves pain in degenerative rheumatic conditions: Patients who took watery extract of devil's claw had as much pain relief as patients who took a chemical defined antiinflammatory medication 1
  • antiinflammatory action (in vitro) 2


  • clearly better tolerated compared to synthetic pain killers 1
  • No known drug interactions associated with Doloteffin, meaning, Doloteffin can be combined with other pain medications.
  • The supportive therapy with Devils claw can help to minimize side effects and to strengthen patient's health.
  • Due to the excellent safety profile of Doloteffin, it can also be used to support long-term treatment.


The particular feature of Doloteffin:
Aqueous extract of the root of Devil's claw

  • In contrast to alcoholic extracts, aqueous extracts of Devil’s claw as in Doloteffin lead to specific lowering of a central inflammatory mediator (Interleukin Il-1 beta). 3


Established Phytopharmaceutical

Doloteffin is a modern medicinal plant product. It is designated to combine the broad clinical experiences of a traditional used medicinal plant with a contemporary GMP-conform presented outstanding product, therefore meeting highly established product standards of safety and quality. 
Doloteffin is manufactured in Germany.

* WHO guidelines on good agricultural and collection practices for medicinal plants.
EMEA guideline on good agricultural and collection practices (GACP) for starting materials of herbal origin.

1. Chrubasik et al., 2003
2. Tippler et al., 1996
3. Fiebich et al., 2001; Chrubasik et al., 2002